After being appointed by former President Donald J. Trump to serve as the U.S. Permanent Representative to the Organization of American States, Trujillo was unanimously confirmed by the United States Senate and served as Ambassador from March 30, 2018 until January 20, 2021. During his time at the OAS, Trujillo served as Chair of the Permanent Council, Budget Committee and the Economic Development Committee. He also led the effort to re-elect Secretary General Luis Almagro.

Trujillo also was appointed by President Trump and served as a Representative of the United States to the 72nd General Assembly of the United Nations under former Ambassador Nikki Haley and was nominated to serve as Assistant Secretary of State for the Western Hemisphere. Trujillo, a native Spanish speaker, is known for his strong ties to the Hispanic community, legal acumen and leadership, and has a wealth of knowledge and connections in Latin American politics.

Prior to serving as Ambassador, Trujillo was elected as State Representative for the 105th District in the Florida House of Representatives, where he served in various capacities, including as Chairman of the Florida House Appropriations Committee, he appropriated and oversaw an $83.5 billion dollar budget. He also served as Chair of the Economic Development Subcommittee, and Chair of Criminal Justice Subcommittee.

Trujillo was a Founding Partner of Trujillo, Vargas, Gonzalez and Hevia LLP, based in Coral Gables, Florida. Under his leadership, the firm grew to more than 50 employees and generated over $10 million in annual revenue. Previously, Trujillo served as Assistant State Attorney, Miami Dade County State Attorney’s Office, Miami, Florida (2007–2011) where he served as a training attorney and Felony Prosecutor.

He currently serves as a member and manager of multiple real-estate holding companies in Coral Gables, Florida, and has also served as a Board Member on the Public Health Trust of Jackson Memorial Hospital, Miami, Florida (2015–2016) and as a member of the Electoral College in 2016.

Trujillo earned a B.S. in Business Administration from Spring Hill College in Mobile, Alabama (2004) and a J.D. from Florida State University College of Law, Tallahassee, Florida (2007). He is an active member of the Florida Bar since 2007 and received an AV rating by Martindale-Hubbell. He is married to Carmen Maria Mir and they have four children: Carlos, Isabella, Juan Pablo and Felipe.